Search on: DIHYDRO-OROTATE OXIDASE 
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Descriptor English:   Dihydroorotate Oxidase 
Descriptor Spanish:   Dihidroorotato Oxidasa 
Descriptor Portuguese:   Di-Hidrorotato Oxidase 
Synonyms English:   Dihydro-Orotate Oxidase
Dihydro Orotate Oxidase
Oxidase, Dihydro-Orotate
Oxidase, Dihydroorotate  
Tree Number:   D08.811.682.660.300
Definition English:   An enzyme that in the course of pyrimidine biosynthesis, catalyzes the oxidation of dihydro-orotic acid to orotic acid utilizing oxygen as the electron acceptor. This enzyme is a flavoprotein which contains both FLAVIN-ADENINE DINUCLEOTIDE and FLAVIN MONONUCLEOTIDE as well as iron-sulfur centers. EC 1.3.3.1. 
History Note English:   94; was DIHYDRO-OROTATE OXIDASE 1977-93 (see under OXIDOREDUCTASES 1977-90); DIHYDRO-OROTATE DEHYDROGENASE & OROTATE REDUCTASE were see DIHYDRO-OROTATE OXIDASE 1977-93 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   31730 
Unique Identifier:   D004081 

Occurrence in VHL:
 

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